Temperature effect on the porosity of hydroxyapatite scaffolds and its use in tissue engineering

Authors

  • Vareska Lucero Zarate-Córdova Facultad de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana, Baja California, México.
  • Dra. Mercedes Teresita Oropeza-Guzmán Centro de Graduados, Instituto Tecnológico de Tijuana, Tijuana, Baja California, México.
  • Eduardo Alberto López-Maldonado Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Tijuana, Baja California, México.
  • Ana Leticia Iglesias Facultad de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana, Baja California, México
  • Dr. Theodore Ng Oakland Oral and Maxillofacial Surgery, Oakland, California, United States.
  • Dr. Eduardo Serena-Gómez Facultad de Ciencias de la Salud, Universidad Autónoma de Baja California, Tijuana, México
  • Graciela Lizeth Pérez González Facultad de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana, Baja California, México
  • Luis Jesús Villarreal-Gómez Facultad de Ciencias de la Ingeniería y Tecnología (FCITEC), Universidad Autónoma de Baja California, Unidad Valle de las Palmas, Tijuana, Baja California, México.

DOI:

https://doi.org/10.37636/recit.v34213221

Keywords:

Hydroxyapatite, porous scaffold, salt leaching method

Abstract

The search for a suitable bone replacement is of great importance due to the difficulty to use autologous transplants. Hence, the objective of this work is to compare the temperature effect on the porosity and average pore diameter of hydroxyapatite porous scaffolds fabricated by the salt leaching method.  Hydroxyapatite porous scaffolds fabricated by the salt leaching technique were sintered from ~150 to 1000 °C. Synthesized hydroxyapatite was assessed by X-ray diffraction (XRD). Zeta potential at different temperatures was evaluated. Specimens were characterized using scanning electron microscopy (SEM) and Raman analysis. The results showed that significant porosity (57%) and pore size (49 µm) occurred with a thermal treatment above ~ 850 °C for scaffolds that were pre-sintered at 1050 °C.

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References

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Micrographies of sHA scaffolds with different heat treatment for 2 hours at 15 KV of magnification. (A) ~150 ᴼC at 2 h (B) ~850 ᴼC at 2 h (C) ~1000 ᴼC at 2 h (D) ~150 ᴼC at 24 h (E) ~850 ᴼC at 24 h (F) ~1000 ᴼC at 24 h.

Published

2020-12-29

How to Cite

Zarate-Córdova, V. L., Oropeza-Guzmán, M. T., López-Maldonado, E. A. ., Iglesias, A. L., Ng, T., Serena-Gómez, E., Pérez-González, G. L., & Villarreal-Gómez, L. J. (2020). Temperature effect on the porosity of hydroxyapatite scaffolds and its use in tissue engineering. REVISTA DE CIENCIAS TECNOLÓGICAS, 3(4), 213–221. https://doi.org/10.37636/recit.v34213221

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